Hi, I'm Brice

I'm a Ph.D. student in Jeff Skolnick's lab, the Center for the Study of Systems Biology at Georgia Tech.

My work is supported by the NSF GRFP (2026 cohort).

Current Research

My doctoral research aims to improve our understanding of pain as a multiscale nervous-system phenomenon.

I study how biological signals are detected, transmitted, transformed, and maintained across levels of organization, from molecular interactions and sensory neurons to peripheral tissues and brain-wide circuits.

My work uses computational and data-driven systems biology to connect mechanisms of peripheral neuropathy, pain persistence, treatment response, and neuropsychiatric disease.

By integrating molecular, cellular, tissue-level, and neuroimaging data, I aim to identify clearer disease states, better biomarkers, and more precise therapeutic strategies for conditions ranging from chronic pain to disorders of brain-circuit regulation.

Selected Projects:

• Valsci
  • Open-source automated scientific literature review tool.
  • Created for the CSSB to facilitate validation of predictions generated by bioinformatics models.
  • Check out the accompanying publication in BMC Bioinformatics.
• I Said, You Heard for iOS
  • An iOS app created for Kind Words Are Cool, LLC.
  • A virtual communication coach and central hub of content for the I Said This, You Heard That books.
• I Said, You Heard - Assessment
  • An online temperament assessment created for Kind Words Are Cool, LLC.
  • Built as a companion tool for the I Said This, You Heard That books.
• Remi Journal (sadly now deprecated)
  • Your personal AI biographer and companion.
  • Hundreds of users and 4.8 stars on the App Store.
  • A production-ready, scalable iOS app built with Flutter, Firebase, Google Cloud Platform, and various AI models.
• CUDAGlycolysis
  • A GPU-powered simulation of glycolysis at the nanometer and microsecond scale.
  • Up to 100,000,000 molecules successfully simulated on an NVIDIA RTX 3070.
• What That Langs (sadly now deprecated)
  • A C++ loopback utility that can transcribe and translate any audio playing on your Windows machine.
  • (Not currently maintained, but let me know if you want to use it and I can boot the server for you)

Publications:

• B Edelman, H Kim, J Skolnick (2026). Scalable discovery and validation of order-specific electronic health record event trajectories for interpretable adverse-outcome risk estimation. Journal of Biomedical Informatics 177, 105008.
• H Zhou, B Edelman, J Skolnick (2026). MENDELSEEK: An algorithm that predicts mendelian genes and elucidates what makes them special. PLOS Computational Biology 22 (2), e1013992.
• B Edelman, J Skolnick (2025). Valsci: an open-source, self-hostable literature review utility for automated large-batch scientific claim verification using large language models. BMC Bioinformatics 26 (1), 140.
• J Skolnick, B Srinivasan, S Skolnick, B Edelman, H Zhou (2025). Entabolons: How Metabolites Modify the Biochemical Function of Proteins and Cause the Correlated Behavior of Proteins in Pathways. Journal of Chemical Information and Modeling 65 (11), 5785-5800.
• H Zhou, B Edelman, J Skolnick (2025). A mode of action protein based approach that characterizes the relationships among most major diseases. Scientific Reports 15 (1), 9668.

Preprints:

• B Edelman, J Skolnick (2026). A reliability-screened thalamocortical control-network phenotype tracks cocaine-use history in cocaine use disorder. medRxiv preprint.